2021 Red Sox Schedule
*** All Times Eastern. ***
| Date | Opponent | Pre-Game | First Pitch |
| Thu, 4/1 | Orioles | 1:10p | 2:10p |
| Fri, 4/2 | NO GAME | ||
| Sat, 4/3 | Orioles | 12:10p | 1:10p |
| Sun, 4/4 | Orioles | 12:10p | 1:10p |
| Mon, 4/5 | Rays | 6:10p | 7:10p |
| Tue, 4/6 | Rays | 6:10p | 7:10p |
| Wed, 4/7 | Rays | 12:10p | 1:10p |
| Thu, 4/8 | @ Orioles | 2:05p | 3:05p |
| Fri, 4/9 | NO GAME | ||
| Sat, 4/10 | @ Orioles | 12:05p | 1:05p |
| Sun, 4/11 | @ Orioles | 12:05p | 1:05p |
| Mon, 4/12 | @ Twins | 6:40p | 7:40p |
| Tue, 4/13 | @ Twins | 6:10p | 7:40p |
| Wed, 4/14 | @ Twins | 6:40p | 7:40p |
| Thu, 4/15 | @ Twins | 12:10p | 1:10p |
| Fri, 4/16 | White Sox | 6:10p | 7:10p |
| Sat, 4/17 | White Sox | 3:05p | 4:05p |
| Sun, 4/18 | White Sox | 12:10p | 1:10p |
| Mon, 4/19 | White Sox | 10:10p | 11:10p |
| Tue, 4/20 | Blue Jays | 6:10p | 7:10p |
| Wed, 4/21 | Blue Jays | 6:10p | 7:10p |
| Thu, 4/22 | Mariners | 6:10p | 7:10p |
| Fri, 4/23 | Mariners | 6:10p | 7:10p |
| Sat, 4/24 | Mariners | 12:10p | 1:10p |
| Sun, 4/25 | Mariners | 12:10p | 1:10p |
| Mon, 4/26 | NO GAME | ||
| Tue, 4/27 | @ Mets | 6:10p | 7:10p |
| Wed, 4/28 | @ Mets | 5:40p | 6:40p |
| Thu, 4/29 | @ Rangers | 7:05p | 8:05p |
| Fri, 4/30 | @ Rangers | 7:05p | 8:05p |
| Sat, 5/1 | @ Rangers | 6:05p | 7:05p |
| Sun, 5/2 | @ Rangers | 1:35p | 2:35p |
| Mon, 5/3 | NO GAME | ||
| Tue, 5/4 | Tigers | 6:10p | 7:10p |
| Wed, 5/5 | Tigers | 6:10p | 7:10p |
| Thu, 5/6 | Tigers | 12:10p | 1:10p |
| Fri, 5/7 | @ Orioles | 6:05p | 7:05p |
| Sat, 5/8 | @ Orioles | 6:05p | 7:05p |
| Sun, 5/10 | @ Orioles | 12:05p | 1:05p |
| Mon, 5/11 | @ Orioles | 5:35p | 6:35p |
| Tue, 5/11 | Athletics | 6:10p | 7:10p |
| Wed, 5/12 | Athletics | 6:10p | 7:10p |
| Thu, 5/13 | Athletics | 6:10p | 7:10p |
| Fri, 5/14 | Angels | 6:10p | 7:10p |
| Sat, 5/15 | Angels | 3:10p | 4:10p |
| Sun, 5/16 | Angels | 12:10p | 1:10p |
| Mon, 5/17 | NO GAME | ||
| Tue, 5/18 | at Blue Jays | 5:37p | 6:37p |
| Wed, 5/19 | at Blue Jays | 5:37p | 6:37p |
| Thu, 5/20 | at Blue Jays | 5:37p | 6:37p |
| Fri, 5/21 | at Phillies | 6:05p | 7:05p |
| Sat, 5/22 | at Phillies | 6:15p | 7:15p |
| Sun, 5/23 | at Phillies | 12:05p | 1:05p |
| Mon, 5/24 | NO GAME | ||
| Tue, 5/25 | Braves | 6:10p | 7:10p |
| Wed, 5/26 | Braves | 6:10p | 7:10p |
| Thu, 5/27 | NO GAME | ||
| Fri, 5/28 | Marlins | 6:10p | 7:10p |
| Sat, 5/29 | Marlins | 3:10p | 4:10p |
| Sun, 5/30 | Marlins | 12:10p | 1:10p |
| Mon, 5/31 | @ Astros | 3:10p | 4:10p |
| Tue, 6/1 | @ Astros | 7:10p | 8:10p |
| Wed, 6/2 | @ Astros | 7:10p | 8:10p |
| Thu, 6/3 | @ Astros | 1:10p | 2:10p |
| Fri, 6/4 | @ Yankees | 6:05p | 7:05p |
| Sat, 6/5 | @ Yankees | 6:15p | 7:15p |
| Sun, 6/6 | @ Yankees | TBD | TBD |
| Mon, 6/7 | NO GAME | ||
| Tue, 6/8 | Astros | 6:10p | 7:10p |
| Wed, 6/9 | Astros | 6:10p | 7:10p |
| Thu, 6/10 | Astros | 6:10p | 7:10p |
| Fri, 6/11 | Blue Jays | 6:10p | 7:10p |
| Sat, 6/12 | Blue Jays | 3:10p | 4:10p |
| Sun, 6/13 | Blue Jays | 12:10p | 1:10p |
| Mon, 6/14 | Blue Jays | 6:10p | 7:10p |
| Tue, 6/15 | at Braves | 6:20p | 7:20p |
| Wed, 6/16 | at Braves | 6:20p | 7:20p |
| Thu, 6/17 | NO GAME | ||
| Fri, 6/118 | @ Royals | 7:10p | 8:10p |
| Sat, 6/19 | @ Royals | 3:10p | 4:10p |
| Sun, 6/20 | @ Royals | 1:10p | 2:10p |
| Mon, 6/21 | NO GAME | ||
| Tue, 6/22 | @ Rays | 6:10p | 7:10p |
| Wed, 6/23 | @ Rays | 6:10p | 7:10p |
| Thu, 6/24 | @ Rays | 6:10p | 7:10p |
| Fri, 6/25 | Yankees | 6:10p | 7:10p |
| Sat, 6/26 | Yankees | 6:15p | 7:15p |
| Sun, 6/27 | Yankees | TBD | TBD |
| Mon, 6/28 | Royals | 6:10p | 7:10p |
| Tue, 6/29 | Royals | 6:10p | 7:10p |
| Wed, 6/30 | Royals | 6:10p | 7:10p |
| Thu, 7/1 | Royals | 12:10p | 1:10p |
| Fri, 7/2 | @ Athletics | 8:40p | 9:40p |
| Sat, 7/3 | @ Athletics | 6:15p | 7:15p |
| Sun, 7/4 | @ Athletics | 3:07p | 4:07p |
| Mon, 7/5 | @ Angles | 8:38p | 9:38p |
| Tue, 7/6 | @ Angles | 8:38p | 9:38p |
| Wed, 7/7 | @ Angles | 3:07p | 4:07p |
| Thu, 7/8 | NO GAME | ||
| Fri, 7/9 | Phillies | 6:10p | 7:10p |
| Sat, 7/10 | Phillies | 3:10p | 4:10p |
| Sun, 7/11 | Phillies | 12:10p | 1:10p |
| Mon, 7/12 | All Star Break | ||
| Tue, 7/13 | All Star Break | ||
| Wed, 7/14 | All Star Break | ||
| Thu, 7/15 | @ Yankees | 6:08p | 7:08p |
| Fri, 7/116 | @ Yankees | 6:05p | 7:05p |
| Sat, 7/17 | @ Yankees | 6:15p | 7:15p |
| Sun, 7/18 | @ Yankees | 6:08p | 7:08p |
| Mon, 7/19 | @ Blue Jays | 6:07p | 7:07p |
| Tue, 7/20 | @ Blue Jays | 6:07p | 7:07p |
| Wed, 7/21 | @ Blue Jays | 6:07p | 7:07p |
| Thu, 7/22 | Yankees | 6:10p | 7:10 |
| Fri, 7/23 | Yankees | 6:10p | 7:10p |
| Sat, 7/24 | Yankees | 6:15p | 7:15p |
| Sun, 7/25 | Yankees | TBD | TBD |
| Mon, 7/26 | Blue Jays | 6:10p | 7:10p |
| Tue, 7/27 | Blue Jays | 6:10p | 7:10p |
| Wed, 7/28 | Blue Jays | 6:10p | 7:10p |
| Thu, 7/29 | Blue Jays | 6:10p | 7:10p |
| Fri, 7/30 | @ Rays | 6:10p | 7:10p |
| Sat, 7/31 | @ Rays | 5:10p | 6:10p |
| Sun, 8/1 | @ Rays | 12:10p | 1:10p |
| Mon, 8/2 | NO GAME | ||
| Tue, 8/3 | @ Tigers | 6:10p | 7:10p |
| Wed, 8/4 | @ Tigers | 6:10p | 7:10p |
| Thu, 8/5 | @ Tigers | 12:10p | 1:10p |
| Fri, 8/6 | @ Blue Jays | 6:07p | 7:07p |
| Sat, 8/7 | @ Blue Jays | 2:07p | 3:07p |
| Sun, 8/8 | @ Blue Jays | 12:07p | 1:07p |
| Mon, 8/9 | NO GAME | ||
| Tue, 8/10 | Rays | 6:10p | 7:10p |
| Wed, 8/11 | Rays | 6:10p | 7:10p |
| Thu, 8/12 | Rays | 3:10p | 4:10p |
| Fri, 8/13 | Orioles | 6:10p | 7:10p |
| Sat, 8/14 | Orioles | 3:10p | 4:10p |
| Sun, 8/15 | Orioles | 12:10p | 1:10p |
| Mon, 8/16 | NO GAME | ||
| Tue, 8/17 | @ Yankees | 6:05p | 7:05p |
| Wed, 8/18 | @ Yankees | 6:05p | 7:05p |
| Thu, 8/19 | NO GAME | ||
| Fri, 8/20 | Rangers | 6:10p | 7:10p |
| Sat, 8/21 | Rangers | 6:10p | 7:10p |
| Sun, 8/22 | Rangers | 12:10p | 1:10p |
| Mon, 8/23 | NO GAME | ||
| Tue, 8/24 | Twins | 6:10p | 7:10p |
| Wed, 8/25 | Twins | 6:10p | 7:10p |
| Thu, 8/26 | Twins | 6:10p | 7:10p |
| Fri, 8/27 | @ Indians | 6:10p | 7:10p |
| Sat, 8/28 | @ Indians | 3:05p | 4:05p |
| Sun, 8/29 | @ Indians | 12:10p | 1:10p |
| Mon, 8/30 | @ Rays | 6:10p | 7:10p |
| Tue, 8/31 | @ Rays | 6:10p | 7:10p |
| Wed, 9/1 | @ Rays | 6:10p | 7:10p |
| Thu, 9/2 | @ Rays | 6:10p | 6:10p |
| Fri, 9/3 | Indians | 6:10p | 7:10p |
| Sat, 9/4 | Indians | 3:10p | 4:10p |
| Sun, 9/5 | Indians | TBD | TBD |
| Mon, 9/6 | Rays | 12:10p | 1:10p |
| Tue, 9/7 | Rays | 6:10p | 7:10p |
| Wed, 9/8 | Rays | 6:10p | 7:10p |
| Thu, 9/9 | NO GAME | ||
| Fri, 9/10 | @ White Sox | 7:10p | 8:10p |
| Sat, 9/11 | @ White Sox | 6:10p | 7:10p |
| Sun, 9/12 | @ White Sox | 1:10p | 2:10p |
| Mon, 9/13 | @ Mariners | 9:10p | 10:10p |
| Tue, 9/14 | @ Mariners | 9:10p | 10:100p |
| Wed, 9/15 | @ Mariners | 3:10p | 4:10p |
| Thu, 9/16 | NO GAME | ||
| Fri, 9/17 | Orioles | 6:10p | 7:10p |
| Sat, 9/18 | Orioles | 12:10p | 1:10p |
| Sun, 9/19 | Orioles | 12:10p | 1:10p |
| Mon, 9/20 | NO GAME | ||
| Tue, 9/21 | Mets | 6:10p | 7:10p |
| Wed, 9/22 | Mets | 6:10p | 7:10p |
| Thu, 9/23 | NO GAME | ||
| Fri, 9/24 | Yankees | 6:10p | 7:10p |
| Sat, 9/25 | Yankees | 4:10p | 4:10p |
| Sun, 9/26 | Yankees | TBD | TBD |
| Mon, 9/27 | NO GAME | ||
| Tue, 9/28 | @ Orioles | 5:35p | 6:35p |
| Wed, 9/29 | @ Orioles | 5:35p | 6:35p |
| Thu, 9/30 | @ Orioles | 5:35p | 6:135p |
| Fri, 10/1 | @ Nationals | 6:05p | 7:05p |
| Sat, 10/2 | @ Nationals | 3:05p | 4:05p |
| Sun, 10/3 | @ Nationals | 2:05p | 3:05p |